
Breast Cancer
Unlike other tumor types, breast cancer – particularly HR+ breast cancer – must be monitored over a long period of time. Recent studies* have shown that the risk relapse for HR+ breast cancer is higher in years 5-20 post-diagnosis compared to the first 5 years. It is now apparent that traditional clinical and pathologic tools are insufficient to determine high risk of late recurrence.
RaDaR is a ctDNA-based MRD test with applicability in different subtypes of breast cancer and different timepoints.
A growing body of evidence confirms that MRD testing offers significant advantages over traditional monitoring methods and can help detect early signs of disease progression.
In some cases, MRD testing is able to detect recurrence more than a year before it is detectable on imaging, allowing potential intervention while the disease burden is still low and treatable.
RaDaR applicability in breast cancer
- Risk stratification: How likely is it for your patient’s tumor to recur? A positive ctDNA result can mean a high risk of recurrence.
- Recurrence surveillance: Regular monitoring with ctDNA may indicate tumor recurrence, often before imaging results.
Clinical support for ctDNA surveillance in breast cancer
ER = estrogen receptor; HER = human epidermal growth factor receptor; HR = hormone receptor.
References: 1. Elliot MJ, et al. San Antonio Breast Cancer Symposium, 2022. Abstract P6-01-16. 2. Cutts R, et al. AACR 2021 Abstract 536. 3. Lipsyc-Sharf M, et al. J Clin Oncol. 2022;40:2408-2419.

RaDaR has been carefully designed to help you detect tumor DNA in the blood with exceptional sensitivity and specificity
- Increased accuracy with a tumor-informed, personalized panel design: RaDaR sequencing assays monitor up to 48 tumor-specific mutations, unique to each patient’s tumor, to help detect circulating tumor DNA (ctDNA)
- Earlier detection with high sensitivity: RaDaR can detect extremely low levels of ctDNA in the blood, with a demonstrated LoD95 = 0.001% VAF. This can give additional time for important treatment management decisions
- Fewer false positives with high specificity: RaDaR has a demonstrated analytical specificity of 100% in validation studies, giving you the confidence that comes from having more reliable results
NeoGenomics has been supporting oncologists and pathologists in their goal to provide patients with the best care possible since 2002.
LoD95 = limit of detection, working at a confidence of 95%; VAF = variant allele fraction.
How to order a RaDaR test

CLIENT SERVICES
NeoGenomics prides itself on its unparalleled customer support team. If you have questions regarding test information, specimen requirements, turnaround times, test add-on, and test results, please feel free to reach out to a Client Services Advocate at client.services@neogenomics.com or call 866.776.5907, option 3.

ONLINE ORDERING
Online Ordering streamlines and simplifies your test-ordering process into a single time-saving, easy-to-use experience.

PAPER ORDER FORMS
Complete a RaDaR test requisition form.
New to NeoGenomics? Call the NeoGenomics Client Services team at 866.776.5907 and press 3 to set up an account.
Investigator-Initiated Trials
NeoGenomics recognizes the important role of externally driven scientific research to expand medical knowledge and define the clinical utility of our tests in a real-world setting.
Get started with RaDaR
Contact us to order a RaDaR test.